Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOX1 | Q9Y5S8 | 12/20 | 1.00 |
| ▸ | BCHE | P06276 | 3/20 | 1.00 |
| ▸ | ACHE | P22303 | 3/20 | 1.00 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | GAA | P10253 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | SNCA | P37840 | 3/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.65 |
| ▸ | MAOA | P21397 | 1/20 | 0.65 |
| ▸ | CNR1 | P21554 | 1/20 | 0.65 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.65 |
| ▸ | HTR2C | P28335 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29384266 | 1.00 | NOX1 (1.00) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL28679021 | 0.98 | NOX1 (0.96) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL28232162 | 0.98 | NOX1 (0.96) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL1509893 | 0.92 | NOX1 (0.84) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL28117966 | 0.90 | NOX1 (0.81) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL4670416 | 0.89 | NOX1 (0.79) | NOX1BCHEACHEMAPTGAA | |
| Urea SCHEMBL27590816 | 0.89 | NOX1 (0.79) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL30769670 | 0.89 | NOX1 (0.79) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL239261 | 0.89 | NOX1 (0.79) | NOX1BCHEACHEMAPTGAA | |
| SCHEMBL28117917 | 0.86 | NOX1 (0.76) | NOX1BCHEACHEMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 477 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250255879-A1 | PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2025-08-14 | — | — | US | claimed |
| CN-119751437-A | Synthesis method of Se-deuterated methyl-thioridazine compound | 浙江工业大学 | 2025-04-04 | — | — | CN | claimed |
| CN-118930860-A | Preparation method of polymer containing sulfonyl and sulfonic acid | 太原理工大学 | 2024-11-12 | — | — | CN | claimed |
| US-20230330095-A1 | PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR | SEOUL NATIONAL UNIVERSITY R&DB FOUNDATION (KR) | 2023-10-19 | — | — | US | claimed |
| EP-4260861-A1 | PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR | Seoul National University R & DB Foundation (KR) | 2023-10-18 | — | — | EP | claimed |
| CN-112954836-B | Electrothermal film based on graphene electrothermal and preparation method thereof | 张标 | 2023-09-29 | — | — | CN | claimed |
| CN-113109474-B | Method for detecting sedative drug metabolism residues in animal tissues | 吉林省农业科学院 | 2023-08-01 | — | — | CN | claimed |
| CN-113512033-B | Phenoxazine and phenothiazine covalent triazine framework material, and preparation method and application thereof | 南京工业大学 | 2023-06-16 | — | — | CN | claimed |
| CN-114574147-A | Solvent-free polyurethane adhesive | 陈文娟 | 2022-06-03 | — | — | CN | claimed |
| CN-113429366-B | Preparation method of chlorpromazine hydrochloride | 常州康普药业有限公司 | 2022-03-08 | — | — | CN | claimed |
| WO-2008027345-A2 | COMBINED γ-SECRETASE INHIBITOR AND PHENOTHIAZINE DERIVATIVE TREATMENT OF NEURODEGENERATIVE DISEASES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-03-06 | — | — | WO | claimed |
| CN-1255390-C | Preparation of 2-cyanophenthiazine | UNIV SHANXI (CN) | 2006-05-10 | — | — | CN | claimed |
| US-20050209173-A1 | Neurodegenerative protein aggregation inhibition methods and compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2005-09-22 | — | — | US | claimed |
| CN-1583732-A | Preparation of 2-cyanophenthiazine | UNIV SHANXI (CN) | 2005-02-23 | — | — | CN | claimed |
| WO-2005011610-A2 | NEURODEGENERATIVE PROTEIN AGGREGATION INHIBITION METHODS AND COMPOUNDS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2005-02-10 | — | — | WO | claimed |
| US-5391465-A | Using phenothiazine or phenoxazine compounds | ROHM AND HAAS COMPANY (US) | 1995-02-21 | — | — | US | claimed |
| CN-1048931-A | In the acid hardening photoresist of high resolution, adopt the method for the Photoactive compounds of selecting by near ultraviolet radiation | ROHM & HAAS (US) | 1991-01-30 | — | — | CN | claimed |
| EP-0404499-A2 | Photosensitive compositions comprising selected photoactive materials and their use in producing high resolution, photoresist images with near ultraviolet radiation | ROHM AND HAAS COMPANY (US) | 1990-12-27 | — | — | EP | claimed |
| US-4407800-A | TRYPANOCIDES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1983-10-04 | — | — | US | claimed |
| US-4249003-A | Process for polycyclic amines | AKTIEBOLAGET LEO (SE) | 1981-02-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330095-A1 | PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR | NUP205, NUP50, NUP188 | NOX1 3666/4885BCHE 3903/4885ACHE 4269/4885 |
| US-20250255879-A1 | PHARMACEUTICAL COMPOSITION FOR ANTI-CANCER COMPRISING NUPR1 ISOFORM A INHIBITOR | NUP205, NUP188, NUP50 | NOX1 3568/4885BCHE 4097/4885ACHE 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.