Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Morpholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL668275 | 0.98 | MEN1 (0.50) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL1509059 | 0.95 | MEN1 (0.48) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL6941937 | 0.95 | MEN1 (0.48) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28395409 | 0.95 | MEN1 (0.48) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28640639 | 0.93 | MEN1 (0.46) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28565361 | 0.93 | MEN1 (0.46) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL29123850 | 0.91 | MEN1 (0.44) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL546850 | 0.85 | MEN1 (0.42) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL3330271 | 0.84 | MEN1 (0.50) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL3318867 | 0.84 | MEN1 (0.41) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115558702-B | Colorimetric detection method for escherichia coli in milk | 合肥工业大学 | 2025-04-22 | — | — | CN | claimed |
| CN-119606858-A | Microneedle dressing for repairing diabetic wound surface and preparation method thereof | 深圳大学 | 2025-03-14 | — | — | CN | claimed |
| CN-118667745-A | Preparation method of cowpea protoplast | 江汉大学 | 2024-09-20 | — | — | CN | claimed |
| CN-118303424-A | Application of silicon dioxide nano pesticide in preventing and treating plant diseases | 武汉科技大学 | 2024-07-09 | — | — | CN | claimed |
| CN-116590008-B | Background elimination-based ratio fluorescent probe for escherichia coli O157: H7 detection and preparation method thereof | 合肥工业大学 | 2024-03-19 | — | — | CN | claimed |
| CN-117431202-A | Separation and instantaneous transformation method for aconitum kusnezoffii protoplast | 昆明理工大学 | 2024-01-23 | — | — | CN | claimed |
| CN-116590008-A | Background elimination-based ratio fluorescent probe for escherichia coli O157: H7 detection and preparation method thereof | 合肥工业大学 | 2023-08-15 | — | — | CN | claimed |
| CN-114917352-B | Drug-loaded disc particles with functions of adhering and regulating macrophages, and preparation method and application thereof | 西南交通大学 | 2023-08-01 | — | — | CN | claimed |
| CN-115851609-A | Listeria monocytogenes P60 monoclonal antibody, immunomagnetic beads and application | 中国科学院微生物研究所 | 2023-03-28 | — | — | CN | claimed |
| CN-115558702-A | Colorimetric detection method for escherichia coli in milk | 合肥工业大学 | 2023-01-03 | — | — | CN | claimed |
| CN-114917352-A | Drug-loaded disc particle with functions of adhering and regulating macrophages as well as preparation method and application thereof | 西南交通大学 | 2022-08-19 | — | — | CN | claimed |
| CN-114432459-A | Peroxidase nanoenzyme-glucose oxidase double-enzyme compound, preparation method and application thereof | 吉林大学 | 2022-05-06 | — | — | CN | claimed |
| CN-110157406-B | Near-infrared quantum dot probe for tracing brain glioma | 温州医科大学 | 2022-03-08 | — | — | CN | claimed |
| CN-110193087-B | Tumor microenvironment response type diagnosis and treatment integrated nanoprobe and preparation method thereof | 山西医科大学 | 2022-02-08 | — | — | CN | claimed |
| CN-113325055-A | Polyacrylamide gel electrophoresis buffer system and application thereof | 中国人民解放军空军军医大学 | 2021-08-31 | — | — | CN | claimed |
| CN-110846380-A | High-accuracy high-density lipoprotein cholesterol detection kit | 潍坊泽成生物技术有限公司 | 2020-02-28 | — | — | CN | claimed |
| CN-110743012-A | Preparation method and application of glucose oxidase modified mesoporous manganese dioxide pharmaceutical composition | 新乡医学院 | 2020-02-04 | — | — | CN | claimed |
| CN-106730008-B | Anal fistula patch or plug, preparation method and application thereof | 北京桀亚莱福生物技术有限责任公司 | 2019-12-24 | — | — | CN | claimed |
| CN-119553490-B | Sericin in-situ reduction silver-loaded PET fiber and preparation method and application thereof | 安徽农业大学 | 2025-06-13 | — | — | CN | disclosed |
| CN-106234415-A | IDA mature polypeptide plant senescence accelerator, preparation method and application | 中国农业科学院烟草研究所 | 2016-12-21 | — | — | CN | disclosed |