Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of Morpholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL28395409 | 0.98 | MEN1 (0.48) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL6941937 | 0.98 | MEN1 (0.48) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28118007 | 0.98 | MEN1 (0.48) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL1509059 | 0.98 | MEN1 (0.48) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28640639 | 0.96 | MEN1 (0.46) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL28565361 | 0.96 | MEN1 (0.46) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL29123850 | 0.94 | MEN1 (0.44) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL546850 | 0.87 | MEN1 (0.42) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL3330271 | 0.86 | MEN1 (0.50) | MEN1KMT2AKDM4EGAACYP2C9 | |
| Morpholine SCHEMBL3318867 | 0.86 | MEN1 (0.41) | MEN1KMT2AKDM4EGAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1738 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121197040-B | In-situ carrier hydrogel based on nano bottle packaging technology and preparation method and application thereof | 上海大学 | 2026-05-19 | — | — | CN | claimed |
| CN-122005951-A | Self-pumping support material with double-layer heterogeneous structure and preparation method and application thereof | 暨南大学 | 2026-05-12 | — | — | CN | claimed |
| CN-116212120-B | Injectable self-healing hydrogel for bone repair and preparation method and application thereof | 武汉轻工大学 | 2025-06-17 | — | — | CN | claimed |
| CN-119607256-B | Collagen dressing with temperature-sensitive performance and preparation method thereof | 湖南汉方康养药业有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119859284-A | Single-molecule device based on supermolecule induced electrochemical polymerization and preparation method thereof | 南开大学 | 2025-04-22 | — | — | CN | claimed |
| CN-119607256-A | Collagen dressing with temperature-sensitive performance and preparation method thereof | 湖南汉方康养药业有限公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119431793-A | Magnetic fluorescent gold nanocluster molecularly imprinted polymer and preparation method and application thereof | 安徽大学 | 2025-02-14 | — | — | CN | claimed |
| CN-119391827-A | MiRNA detection method | 南京医科大学第二附属医院 | 2025-02-07 | — | — | CN | claimed |
| CN-118050500-B | Clostridium perfringens alpha toxin electrochemical immunosensor and preparation and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2024-12-06 | — | — | CN | claimed |
| CN-119060271-A | Contact lens material containing macromolecular biological protein monomer and preparation method and application thereof | 慈溪市人民医院医疗健康集团(慈溪市人民医院) | 2024-12-03 | — | — | CN | claimed |
| WO-2008134200-A1 | HIGH EFFICIENCY ELECTROPORATION BUFFER | BIO-RAD LABORATORIES, INC. (US) | 2008-11-06 | — | — | WO | claimed |
| US-20080268542-A1 | High Efficiency Electroporation Buffer | BIO-RAD LABORATORIES, INC. (US) | 2008-10-30 | — | — | US | claimed |
| US-20080039356-A1 | Selective removal chemistries for semiconductor applications, methods of production and uses thereof | HONEYWELL INTERNATIONAL INC. | 2008-02-14 | — | — | US | claimed |
| US-7052535-B2 | Additives to eliminate bronzing of inkjet ink formulations on specialty quick-dry inkjet photographic media | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2006-05-30 | — | — | US | claimed |
| WO-2005012447-A1 | ADDITIVES TO ELIMINATE BRONZING OF INKJET INK FORMULATIONS ON SPECIALTY QUICK-DRY INKJET PHOTOGRAPHIC MEDIA | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) | 2005-02-10 | — | — | WO | claimed |
| US-20050025914-A1 | Additives to eliminate bronzing of inkjet ink formulations on specialty quick-dry inkjet photographic media | HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. | 2005-02-03 | — | — | US | claimed |
| US-5350694-A | Composition method and device for measuring the divalent cation concentration or specific gravity of a test sample | MILES INC. (US) | 1994-09-27 | — | — | US | claimed |
| US-5320969-A | Measuring the change in color when complexing a metal compound and colored indicator in a buffered solution of biological sample, e.g. urine | MILES INC. (US) | 1994-06-14 | — | — | US | claimed |
| US-5302531-A | Mixture of complexing agent, metal compound and indicator | MILES INC. (US) | 1994-04-12 | — | — | US | claimed |
| US-5089420-A | With an indicator dye, a hydroperoxide and a buffer; especially useful for assaying accult blood | MILES INC. (US) | 1992-02-18 | — | — | US | claimed |