Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.77 |
| ▸ | PKM | P14618 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | NQO2 | P16083 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070213 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL31415566 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL1104817 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL31070206 | 0.88 | KDM4E (1.00) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL825060 | 0.86 | KDM4E (0.96) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL12553477 | 0.86 | KDM4E (0.96) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL18083001 | 0.84 | ALDH1A1 (0.93) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL21397101 | 0.84 | ALDH1A1 (0.93) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL28118425 | 0.83 | ALDH1A1 (0.77) | KDM4EALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL15383403 | 0.83 | KDM4E (0.54) | KDM4EALDH1A1L3MBTL1PKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432108-A | Hydrazone compound containing methyl quinoxaline structure, preparation method and application thereof | 浙江工业大学 | 2017-02-22 | — | — | CN | claimed |
| CN-106432108-A | Hydrazone compound containing methyl quinoxaline structure, preparation method and application thereof | 浙江工业大学 | 2017-02-22 | — | — | CN | disclosed |
| CN-106234373-A | A kind of hydrazone compounds containing methyl benzopyrazines structure is as the application of antibacterial | 浙江工业大学 | 2016-12-21 | — | — | CN | disclosed |