Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32667194 | 1.00 | OPRM1 (0.38) | OPRM1OPRD1OPRK1OPRL1DDB1 | |
| SCHEMBL12539968 | 0.89 | MAPK1 (0.44) | OPRM1OPRD1OPRK1OPRL1DDB1 | |
| Hydrochloric Acid SCHEMBL2630820 | 0.87 | MAPK1 (0.43) | OPRM1OPRD1OPRK1OPRL1DDB1 | |
| SCHEMBL30200047 | 0.84 | ALDH1A1 (0.42) | OPRM1OPRD1OPRK1OPRL1DDB1 | |
| SCHEMBL527848 | 0.81 | ALDH1A1 (0.40) | OPRM1OPRD1OPRK1OPRL1DDB1 | |
| SCHEMBL659325 | 0.78 | KDM4E (0.48) | OPRM1OPRD1OPRK1OPRL1DDB1 | |
| SCHEMBL900225 | 0.78 | — | — | |
| SCHEMBL29448519 | 0.78 | — | — | |
| SCHEMBL15202095 | 0.76 | ALDH1A1 (0.42) | OPRM1OPRD1OPRK1OPRL1DDB1 | |
| SCHEMBL31252018 | 0.74 | KDM4E (0.37) | ALDH1A1MAPK1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104169281-B | The pyrroles's diformamide condensed and they are as the purposes of medicine | 赛诺菲 | 2016-12-14 | — | — | CN | disclosed |