Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259334 | 0.85 | ALDH1A1 (0.44) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27936928 | 0.78 | ESR1 (0.42) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL22912503 | 0.78 | PIK3CD (0.38) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL27767221 | 0.76 | GBA1 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL7282981 | 0.76 | SYK (0.40) | ALDH1A1KDM4E | |
| SCHEMBL28089027 | 0.76 | GRM2 (0.37) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL28139174 | 0.76 | CA12 (0.36) | KDM4E | |
| SCHEMBL28065313 | 0.74 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL27872052 | 0.74 | MEN1 (0.31) | ALDH1A1 | |
| SCHEMBL28114840 | 0.74 | NAAA (0.40) | ALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106188043-A | Tetracyclic compound | 梅迪维新技术公司 | 2016-12-07 | — | — | CN | disclosed |