Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26933019 | 0.78 | MAOB (0.53) | MAOBMAOADDB1CRBNRAB9A | |
| SCHEMBL27318766 | 0.77 | KDM1A (0.44) | MAOBMAOAKDM1A | |
| SCHEMBL12188964 | 0.72 | MAOB (0.50) | MAOBMAOADDB1CRBNRAB9A | |
| SCHEMBL13888944 | 0.72 | MAOB (0.50) | MAOBMAOADDB1CRBNRAB9A | |
| SCHEMBL11718044 | 0.71 | MAOB (0.46) | MAOBMAOADDB1CRBNRAB9A | |
| SCHEMBL27771288 | 0.71 | MAOA (0.47) | MAOBMAOADDB1CRBNRAB9A | |
| SCHEMBL4337820 | 0.71 | MEN1 (0.63) | MAOBMAOADDB1CRBNRAB9A | |
| SCHEMBL9430213 | 0.70 | KDM1A (0.36) | KDM1A | |
| SCHEMBL9196143 | 0.70 | KDM1A (0.36) | KDM1A | |
| SCHEMBL31090897 | 0.70 | KDM1A (0.40) | MAOBMAOADDB1CRBNRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103373911-B | Single fluoro cyclopropanes compound and its preparation method and application | 中国科学院上海有机化学研究所 | 2016-12-14 | — | — | CN | disclosed |