Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM1A | O60341 | 2/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4337820 | 0.80 | MEN1 (0.63) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL26933019 | 0.80 | MAOB (0.53) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL13888944 | 0.74 | MAOB (0.50) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL12188964 | 0.74 | MAOB (0.50) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL27771288 | 0.72 | MAOA (0.47) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL28118338 | 0.71 | MAOB (0.45) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL24529592 | 0.69 | ALDH1A1 (0.43) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL17410964 | 0.69 | MAPT (0.47) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL27181178 | 0.69 | ALDH1A1 (0.43) | MAOBMAOAMEN1RAB9AKMT2A | |
| SCHEMBL28829917 | 0.68 | MAOB (0.43) | MAOBMAOAMEN1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4035426-A | Diarylcyclobutanes | MEAD JOHNSON & COMPANY (US) | 1977-07-12 | — | — | US | disclosed |
| US-3939196-A | Diarylcyclobutanes | MEAD JOHNSON & COMPANY (US) | 1976-02-17 | — | — | US | disclosed |