Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2490075 | 0.73 | CYP3A4 (0.45) | CYP11B1CYP11B2TSHRCYP3A4CYP1A2 | |
| SCHEMBL27547431 | 0.71 | TBXAS1 (0.39) | CYP11B1CYP11B2ALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL5332293 | 0.69 | CYP3A4 (0.37) | CYP11B1CYP11B2TSHRALDH1A1CYP3A4 | |
| SCHEMBL3155382 | 0.66 | NFE2L2 (0.46) | CYP11B1CYP11B2ALDH1A1CYP3A4CYP1A2 | |
| P-Xylene SCHEMBL29257669 | 0.64 | CYP19A1 (0.47) | CYP11B1CYP11B2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL872215 | 0.64 | IDO1 (0.61) | CYP11B1CYP11B2TSHRALDH1A1CYP3A4 | |
| P-Xylene SCHEMBL29257667 | 0.63 | CYP19A1 (0.46) | CYP11B1CYP11B2ALDH1A1TDP1HSD17B10 | |
| SCHEMBL8927292 | 0.63 | TBXAS1 (0.48) | CYP11B1CYP11B2TSHRCYP3A4CYP1A2 | |
| P-Xylene SCHEMBL29257668 | 0.63 | CYP19A1 (0.46) | CYP11B1CYP11B2ALDH1A1TDP1HSD17B10 | |
| P-Xylene SCHEMBL29257666 | 0.63 | CYP19A1 (0.46) | CYP11B1CYP11B2ALDH1A1TDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106413756-A | Methods of using anti-STEAP 1 antibodies and immunoconjugates | 豪夫迈·罗氏有限公司 | 2017-02-15 | — | — | CN | disclosed |