Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 4/20 | 0.33 |
| ▸ | CTSK | P43235 | 4/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSB | P07858 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1224366 | 0.84 | MEN1 (0.45) | SYKKMT2AMEN1GAACA12 | |
| SCHEMBL1224364 | 0.84 | MEN1 (0.45) | SYKKMT2AMEN1GAACA12 | |
| SCHEMBL2749935 | 0.84 | MEN1 (0.45) | SYKKMT2AMEN1GAACA12 | |
| SCHEMBL570033 | 0.74 | MEN1 (0.50) | SYKKMT2AMEN1GAACA12 | |
| SCHEMBL4975556 | 0.74 | ACHE (0.50) | ALDH1A1NPC1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL3683917 | 0.74 | MEN1 (0.47) | SYKKMT2AMEN1GAACA12 | |
| SCHEMBL2369074 | 0.73 | MEN1 (0.46) | SYKKMT2AMEN1GAACA12 | |
| SCHEMBL12880606 | 0.73 | MEN1 (0.46) | SYKKMT2AMEN1GAACA12 | |
| SCHEMBL5352030 | 0.73 | MEN1 (0.46) | SYKKMT2AMEN1GAACA12 | |
| SCHEMBL17792645 | 0.72 | CASR (0.44) | SYKKMT2AMEN1GAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317072-A | Heterocyclic compound for treatment of mycobacterial infections and use thereof | 盟科医药技术(上海)有限公司 | 2017-01-11 | — | — | CN | disclosed |