SCHEMBL28118535

SCHEMBL28118535

C=CCO[Si](CNc1ccccc1)(OC)OC

nearest known ligand 0.35

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
FFAR1 O14842 1/20 0.33
ALDH1A1 P00352 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
KCNH3 Q9ULD8 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28332770 0.81 MAPT (0.43) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL114143 0.81 MAPT (0.43) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL28383132 0.80 MAPT (0.38) MAPTALDH1A1MEN1KMT2AKCNH3
SCHEMBL29008630 0.79 MAPT (0.37) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL2811190 0.76 ALOX15 (0.35) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL11444038 0.75 MAPT (0.34) MAPTALDH1A1MEN1KMT2AKCNH3
O-Xylene SCHEMBL27577493 0.75 MAPT (0.39) MAPTSMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL629259 0.73 MAPT (0.38) MAPTSMN1; SMN2ALDH1A1L3MBTL1MEN1
SCHEMBL2802671 0.73 TDP1 (0.34) MAPTALDH1A1MEN1KMT2A
Benzene SCHEMBL29290992 0.72 MEN1 (0.31) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106272851-A The method being raw material production balustrade with Eucalyptus core 广西彬伟装饰材料有限公司 2017-01-04 CN disclosed