Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | BHMT | Q93088 | 3/20 | 0.43 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.42 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.38 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| E388 SCHEMBL27002526 | 1.00 | LMNA (0.78) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL28696 | 0.88 | LMNA (1.00) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL28962323 | 0.88 | LMNA (1.00) | LMNAKMT2AHSD17B10TDP1TSHR | |
| SCHEMBL4337588 | 0.86 | — | — | |
| Thioglycolic Acid SCHEMBL27002512 | 0.86 | TSHR (0.77) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL4194910 | 0.85 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL9715431 | 0.85 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL21494504 | 0.85 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL341724 | 0.85 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR | |
| E388 SCHEMBL5169308 | 0.85 | LMNA (0.93) | LMNAKMT2AHSD17B10TDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106319684-A | Conductive composite fiber materials based on graphene oxide and preparing method thereof | 张伟 | 2017-01-11 | — | — | CN | disclosed |