Phosphoric Acid

Phosphoric Acid

SCHEMBL28118745

C=CCOP(=O)(O)O.O=P(O)(O)O.[NaH]

nearest known ligand 0.47

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Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LPAR3 Q9UBY5 8/20 0.47
LPAR2 Q9HBW0 6/20 0.47
FNTA P49354 3/20 0.39
FNTB P49356 3/20 0.39
MPI P34949 1/20 0.34
TPI1 P60174 2/20 0.33
BTN3A1 O00481 2/20 0.33
LPAR1 Q92633 4/20 0.32
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
FBP1 P09467 1/20 0.31
FDPS P14324 1/20 0.30
BLM P54132 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphoric Acid SCHEMBL28118743 1.00 LPAR3 (0.47) LPAR3LPAR2FNTAFNTBMPI
Phosphoric Acid SCHEMBL27466643 0.97 LPAR3 (0.48) LPAR3LPAR2FNTAFNTBMPI
SCHEMBL787423 0.97
Phosphoric Acid SCHEMBL9397376 0.97 LPAR3 (0.48) LPAR3LPAR2FNTAFNTBMPI
Phosphoric Acid SCHEMBL27650424 0.95 LPAR3 (0.47) LPAR3LPAR2FNTAFNTBMPI
SCHEMBL15847030 0.95 LPAR3 (0.50) LPAR3LPAR2FNTAFNTBMPI
SCHEMBL30321 0.95
Methane SCHEMBL4957355 0.92 LPAR3 (0.48) LPAR3LPAR2FNTAFNTBMPI
SCHEMBL11598005 0.92
Ethylene SCHEMBL6264686 0.92 LPAR3 (0.48) LPAR3LPAR2FNTAFNTBMPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106572957-A Skin color-improving agent and composition for improving skin color 昭和电工株式会社 2017-04-19 CN disclosed