SCHEMBL28118870

SCHEMBL28118870

[CH]=C(c1ccccc1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.54
KMT2A Q03164 3/20 0.54
L3MBTL1 Q9Y468 3/20 0.54
MAPT P10636 2/20 0.54
MEN1 O00255 2/20 0.54
HPGD P15428 2/20 0.54
GAA P10253 1/20 0.54
NPSR1 Q6W5P4 3/20 0.48
RAB9A P51151 4/20 0.40
NPC1 O15118 2/20 0.40
POLB P06746 1/20 0.40
HTT P42858 1/20 0.40
TDP1 Q9NUW8 2/20 0.39
ATM Q13315 1/20 0.39
TRPM8 Q7Z2W7 1/20 0.36
CES2 O00748 2/20 0.36
CES1 P23141 2/20 0.36
DAO P14920 1/20 0.36
TSHR P16473 1/20 0.36
NAPRT Q6XQN6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3900737 0.74 ALDH1A1 (0.58) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL27663422 0.72 ALDH1A1 (0.52) ALDH1A1KMT2AMAPTMEN1HPGD
SCHEMBL2449504 0.70 NPSR1 (0.61) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL8982783 0.70 ALDH1A1 (0.54) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL28613770 0.70 ALDH1A1 (1.00) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL1003807 0.70 NPSR1 (0.61) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL988299 0.70 ALDH1A1 (0.54) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL7093374 0.69 NPSR1 (0.47) ALDH1A1KMT2AL3MBTL1MAPTHPGD
SCHEMBL6707567 0.68 ALDH1A1 (0.52) ALDH1A1KMT2AL3MBTL1MAPTMEN1
SCHEMBL27971567 0.68 ALDH1A1 (0.52) ALDH1A1KMT2AL3MBTL1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106325009-B Photoreceptor, handle box and image forming apparatus 京瓷办公信息系统株式会社 2019-10-18 CN disclosed
CN-109725508-A Polyarylate resin and Electrophtography photosensor 京瓷办公信息系统株式会社 2019-05-07 CN disclosed
CN-106325009-A Electrophotographic photosensitive member, process cartridge, and image forming apparatus 京瓷办公信息系统株式会社 2017-01-11 CN disclosed