Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28118901

CC(C)(C)OC(=O)C(CCO)c1ccccc1.N

nearest known ligand 0.43

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.43
CTSK P43235 3/20 0.40
RIPK1 Q13546 2/20 0.40
CTSS P25774 1/20 0.40
ATM Q13315 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
TRPA1 O75762 1/20 0.39
CHRM1 P11229 1/20 0.38
GAA P10253 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28271058 0.98 AAK1 (0.44) AAK1CTSKRIPK1CTSSATM
SCHEMBL28022205 0.98 AAK1 (0.44) AAK1CTSKRIPK1CTSSATM
SCHEMBL2291108 0.86 CTSK (0.44) AAK1CTSKRIPK1CTSSATM
SCHEMBL28132488 0.83 AAK1 (0.34) AAK1KMT2ALMNA
SCHEMBL2293825 0.83 CTSK (0.51) AAK1CTSKCTSS
SCHEMBL2293652 0.82 MEN1 (0.55) L3MBTL1KMT2AMEN1LMNAGAA
SCHEMBL27524640 0.82 CTSK (0.41) AAK1CTSKRIPK1CTSSATM
SCHEMBL27842492 0.82 CTSK (0.41) AAK1CTSKRIPK1CTSSATM
SCHEMBL27349069 0.82 CTSK (0.41) AAK1CTSKRIPK1CTSSATM
SCHEMBL28124091 0.82 CTSK (0.41) AAK1CTSKRIPK1CTSSATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279354-A A kind of synthetic method of amino acid neural dipeptides 温州医科大学 2017-01-04 CN disclosed