Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.61 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.61 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALPL | P05186 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.51 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.51 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.51 |
| ▸ | ABL1 | P00519 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1422659 | 0.84 | KDM4E (0.67) | CYP11B1CYP11B2CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL8165131 | 0.83 | CYP11B2 (0.61) | CYP11B1CYP11B2CYP19A1CYP17A1PDE4B | |
| SCHEMBL14003313 | 0.83 | CYP11B1 (0.55) | CYP11B1CYP11B2CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL29775388 | 0.83 | CYP11B2 (0.61) | CYP11B1CYP11B2CYP19A1CYP17A1PDE4B | |
| SCHEMBL7369883 | 0.82 | CYP11B1 (0.46) | CYP11B1CYP11B2CYP19A1CYP17A1PDE4B | |
| SCHEMBL2652791 | 0.81 | MKNK1 (0.55) | CYP11B1CYP11B2CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL6217515 | 0.81 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1CYP17A1CYP3A4 | |
| SCHEMBL19418726 | 0.81 | CYP11B1 (0.52) | CYP11B1CYP11B2CYP17A1CYP3A4KMT2A | |
| SCHEMBL5988696 | 0.80 | HPGD (0.65) | KMT2AALPLMEN1POLBKDM4E | |
| SCHEMBL28225240 | 0.80 | MKNK1 (0.60) | CYP11B1CYP11B2CYP19A1CYP17A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397453-A | Materials with aza-dibenzothiophene or aza-dibenzofuran core for PHOLED | 通用显示公司 | 2017-02-15 | — | — | CN | disclosed |