Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 10/20 | 0.61 |
| ▸ | CYP11B1 | P15538 | 9/20 | 0.61 |
| ▸ | CYP17A1 | P05093 | 5/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8165131 | 1.00 | CYP11B2 (0.61) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL14925557 | 0.84 | CYP11B2 (0.74) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL14003313 | 0.84 | CYP11B1 (0.55) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL1423147 | 0.83 | KDM4E (0.69) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL28118939 | 0.83 | CYP11B1 (0.61) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL2652791 | 0.83 | MKNK1 (0.55) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL6217515 | 0.83 | CYP11B1 (0.54) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL28225240 | 0.81 | MKNK1 (0.60) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E | |
| SCHEMBL8502557 | 0.81 | CYP17A1 (0.55) | CYP11B2CYP11B1CYP17A1KDM4ENPC1 | |
| SCHEMBL7372635 | 0.81 | CYP11B2 (0.52) | CYP11B2CYP11B1CYP17A1CYP19A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114761083-B | 5-HT for treating depression 2A Agonists | 罗福拉公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-114761083-A | 5-HT for the treatment of depression2AAgonists | 罗福拉公司 | 2022-07-15 | — | — | CN | disclosed |