Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | HRH1 | P35367 | 2/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23031990 | 0.84 | ACP3 (0.47) | KMT2AMEN1HTTGAAALDH1A1 | |
| SCHEMBL11546777 | 0.80 | KMT2A (0.43) | KMT2AMEN1BRD4ALDH1A1SMN1; SMN2 | |
| SCHEMBL23031983 | 0.80 | ACP3 (0.49) | KMT2AMEN1BRD4HTTALDH1A1 | |
| SCHEMBL409758 | 0.78 | POLB (0.50) | KMT2AMEN1HTTGAALMNA | |
| SCHEMBL23032196 | 0.74 | ACP3 (0.47) | HTTALDH1A1SMN1; SMN2L3MBTL1ATM | |
| SCHEMBL23031987 | 0.73 | ESR1 (0.42) | GAAALDH1A1L3MBTL1ESR1MAPT | |
| SCHEMBL23031984 | 0.73 | GAA (0.46) | KMT2AMEN1HTTGAAALDH1A1 | |
| SCHEMBL14509733 | 0.72 | HTT (0.49) | KMT2AMEN1BRD4HTTNPSR1 | |
| SCHEMBL11045593 | 0.72 | BRD4 (0.43) | KMT2AMEN1BRD4HTTNPSR1 | |
| SCHEMBL14677603 | 0.71 | KMT2A (0.48) | KMT2AMEN1BRD4HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106348990-B | A method of synthesis 1,2,2- triaryl ethyl ketone and its derivative | 兰州大学 | 2019-10-18 | — | — | CN | disclosed |
| CN-106348990-A | Method for synthesizing 1,2,2-triaryl ethyl ketone and derivatives thereof | 兰州大学 | 2017-01-25 | — | — | CN | disclosed |