SCHEMBL28119360

SCHEMBL28119360

[CH2]CC1CCN(C=O)CC1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28206026 0.78 HSD17B10 (0.32) HSD17B10
SCHEMBL17813336 0.76 HSD17B10 (0.31) HSD17B10
SCHEMBL14514193 0.76 HSD17B10 (0.31) HSD17B10
SCHEMBL10638063 0.76 HSD17B10 (0.31) HSD17B10
SCHEMBL2384801 0.76 NCF1 (0.50) HSD17B10
SCHEMBL23516990 0.76 CNR2 (0.35) HSD17B10
SCHEMBL1307333 0.76 HSD17B10 (0.35) HSD17B10
SCHEMBL4524664 0.76
SCHEMBL9633965 0.76 TFPI2 (0.33) HSD17B10
SCHEMBL27869022 0.76 HSD17B10 (0.31) HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104910158-B 5,6,7,8-tetrahydropyrido[3,4-d] pyrimidine compound with bioactivity as well as preparation method and application thereof 河南师范大学 2017-04-12 CN disclosed