Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3127073 | 0.82 | CNR2 (0.30) | — | |
| SCHEMBL10846475 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL11009997 | 0.77 | HSD17B10 (0.31) | HSD17B10 | |
| SCHEMBL14514193 | 0.76 | HSD17B10 (0.31) | HSD17B10 | |
| SCHEMBL1307333 | 0.76 | HSD17B10 (0.35) | TFPI2HSD17B10 | |
| SCHEMBL23516990 | 0.76 | CNR2 (0.35) | HSD17B10 | |
| SCHEMBL17813336 | 0.76 | HSD17B10 (0.31) | HSD17B10 | |
| SCHEMBL2384801 | 0.76 | NCF1 (0.50) | HSD17B10 | |
| SCHEMBL10638063 | 0.76 | HSD17B10 (0.31) | HSD17B10 | |
| SCHEMBL6650415 | 0.73 | CHRM2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5162523-A | CEPHALOSPORIN ANTIBACTERIAL COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 1992-11-10 | — | — | US | disclosed |
| US-5159077-A | Bactericide, antibiotic | HOFFMANN-LA ROCHE INC. (US) | 1992-10-27 | — | — | US | disclosed |
| EP-0409081-A1 | Beta-Lactam Derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-23 | — | — | EP | disclosed |
| US-4605744-A | ANTIBIOTICS | HOFFMANN-LA ROCHE INC. (US) | 1986-08-12 | — | — | US | disclosed |
| US-4537969-A | AZOLE-SUBSTITUTED SATURATED HETEROCYCLIC CARBOXALDEHYDE ACETALS;INTERMEDIATES FOR 6-AMIDINOPENICILLINS | HOFFMANN-LA ROCHE INC. (US) | 1985-08-27 | — | — | US | disclosed |
| EP-0148283-A1 | Novel penicillanic acid derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1985-07-17 | — | — | EP | disclosed |
| US-4431653-A | ANTIBIOTICS; BACTERICIDES; SSYNERGISTIC WITH AMINO ACID DERIVATIVE | HOFFMANN-LA ROCHE INC. (US) | 1984-02-14 | — | — | US | disclosed |
| US-4246262-A | ANTIBIOTICS | LEO PHARMACEUTICAL PRODUCTS, LTD. A/S (DK) | 1981-01-20 | — | — | US | disclosed |