SCHEMBL28119480

SCHEMBL28119480

O=C1C=CC(=O)C(c2ccccc2)=C1.[H+]

nearest known ligand 0.95

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 4/20 0.95
MAOB P27338 4/20 0.95
HSD17B3 P37058 1/20 0.88
BACE1 P56817 4/20 0.58
KDM4E B2RXH2 2/20 0.57
MAPT P10636 2/20 0.57
MEN1 O00255 1/20 0.57
PKM P14618 1/20 0.57
MAPK1 P28482 1/20 0.57
KMT2A Q03164 1/20 0.57
MCL1 Q07820 1/20 0.57
TDP1 Q9NUW8 1/20 0.57
PTPN1 P18031 3/20 0.50
CDC25B P30305 2/20 0.50
PTPRC P08575 1/20 0.50
PTPRF P10586 1/20 0.50
SETD7 Q8WTS6 3/20 0.49
CCR6 P51684 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
PTPN11 Q06124 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26262 0.98 MAOA (1.00) MAOAMAOBHSD17B3BACE1KDM4E
SCHEMBL11329163 0.95 MAOA (0.95) MAOAMAOBHSD17B3BACE1KDM4E
Bromide SCHEMBL27550712 0.95 MAOA (0.95) MAOAMAOBHSD17B3BACE1KDM4E
SCHEMBL10959950 0.93 HSD17B3 (1.00) MAOAMAOBHSD17B3BACE1KDM4E
Ethane SCHEMBL28553030 0.93 MAOA (0.91) MAOAMAOBHSD17B3BACE1KDM4E
SCHEMBL27519851 0.90 MAOA (0.84) MAOAMAOBHSD17B3BACE1KDM4E
SCHEMBL27169536 0.85 HSD17B3 (0.78) MAOAMAOBHSD17B3BACE1KDM4E
SCHEMBL28028117 0.84 HSD17B3 (0.75) MAOAMAOBHSD17B3BACE1KDM4E
SCHEMBL21887168 0.82 MAOA (0.72) MAOAMAOBHSD17B3BACE1KDM4E
Nitrobenzene SCHEMBL27327181 0.82 MAOA (0.70) MAOAMAOBHSD17B3BACE1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661316-B Polycarbonate compositions 沙特基础全球技术有限公司 2019-06-28 CN disclosed
CN-105593281-B Infrared reflective dark colored polycarbonate compositions 沙特基础全球技术有限公司 2018-09-25 CN disclosed
CN-104271668-B Polycarbonate compositions 沙特基础全球技术有限公司 2017-09-01 CN disclosed
CN-107075237-A Bridging property makrolon and the design method by its product formed 沙特基础全球技术有限公司 2017-08-18 CN disclosed
CN-107001689-A Suspension polymerisation composition, method and application thereof 纳米-尺寸科技有限公司 2017-08-01 CN disclosed
CN-106661317-A Polycarbonate compositions 沙特基础全球技术有限公司 2017-05-10 CN disclosed
CN-106661316-A Polycarbonate compositions 沙特基础全球技术有限公司 2017-05-10 CN disclosed
CN-104321380-B Polycarbonate compositions 沙特基础全球技术有限公司 2016-12-28 CN disclosed