SCHEMBL28119671

SCHEMBL28119671

CCCCOc1ccc(C=CCCC(C(=O)O)C(=O)O)cc1

nearest known ligand 0.52

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.51
PPARD Q03181 1/20 0.51
ABCG2 Q9UNQ0 1/20 0.50
AHR P35869 1/20 0.47
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
ALOX5 P09917 2/20 0.45
PPARG P37231 2/20 0.45
ALB P02768 1/20 0.45
BCHE P06276 1/20 0.44
PLA2G4B P0C869 1/20 0.44
SAE1 Q9UBE0 1/20 0.44
UBA2 Q9UBT2 1/20 0.44
PTGES O14684 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8080149 0.84 PPARA (0.61) PPARAPPARDABCG2KDM4EMEN1
SCHEMBL8080152 0.84 PPARA (0.61) PPARAPPARDABCG2KDM4EMEN1
SCHEMBL27993003 0.82 GRIK1 (0.56) BCHE
SCHEMBL10740482 0.81 PPARA (0.57) PPARAPPARDKMT2APPARGALB
SCHEMBL10740476 0.81 PPARA (0.57) PPARAPPARDKMT2APPARGALB
SCHEMBL7999920 0.81 ABCG2 (0.50) PPARAPPARDABCG2AHR
SCHEMBL8080022 0.81 PPARA (0.59) PPARAPPARDABCG2KDM4EMEN1
SCHEMBL8080020 0.81 PPARA (0.59) PPARAPPARDABCG2KDM4EMEN1
SCHEMBL8087464 0.80 PPARA (0.62) PPARAPPARDABCG2KDM4EPPARG
SCHEMBL8087469 0.80 PPARA (0.62) PPARAPPARDABCG2KDM4EPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106459357-B Aromatic nitrile-containing compositions for making transparent polythiourethane articles 科思创德国股份有限公司 2019-07-30 CN disclosed
CN-106459357-A Aromatic nitrile-containing compositions for making transparent polythiourethane articles 科思创德国股份有限公司 2017-02-22 CN disclosed