Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10739398 | 0.90 | MGLL (0.50) | ABCG2MAPTALDH1A1BRD4SMN1; SMN2 | |
| SCHEMBL10739403 | 0.90 | MGLL (0.50) | ABCG2MAPTALDH1A1BRD4SMN1; SMN2 | |
| SCHEMBL20024718 | 0.82 | PPARA (0.53) | LTA4HALDH1A1L3MBTL1PPARA | |
| SCHEMBL8080152 | 0.82 | PPARA (0.61) | ABCG2MAPTALDH1A1L3MBTL1PPARA | |
| SCHEMBL8080149 | 0.82 | PPARA (0.61) | ABCG2MAPTALDH1A1L3MBTL1PPARA | |
| SCHEMBL28119671 | 0.81 | PPARA (0.51) | ABCG2AHRPPARAPPARD | |
| SCHEMBL4202774 | 0.81 | TDP1 (0.50) | MAPTALDH1A1MAPK1PPARA | |
| SCHEMBL4957455 | 0.81 | TDP1 (0.50) | MAPTALDH1A1MAPK1PPARA | |
| SCHEMBL4512879 | 0.80 | LTA4H (0.54) | LTA4HPPARAPPARD | |
| SCHEMBL4512878 | 0.80 | LTA4H (0.54) | LTA4HPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009113320-A1 | MMP INHIBITOR | 株式会社ヤクルト本社 (JP) | 2009-09-17 | — | — | WO | disclosed |