SCHEMBL28121982

SCHEMBL28121982

O=Cc1ncnc(Br)c1F

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.32
TRIM33 Q9UPN9 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4789975 0.68 TRIM24 (0.35) TRIM24TRIM33
SCHEMBL19950129 0.68 TRIM24 (0.31) TRIM24TRIM33
SCHEMBL32679735 0.68 TRIM24 (0.35) TRIM24TRIM33
SCHEMBL21224353 0.65 KCNJ1 (0.31)
SCHEMBL28868626 0.65 KDM4E (0.32) TRIM24TRIM33
SCHEMBL10164764 0.65
SCHEMBL25304518 0.65 KCNJ1 (0.30)
SCHEMBL17512179 0.64 TRIM24 (0.53) TRIM24TRIM33
Water SCHEMBL17748269 0.63 TRIM24 (0.52) TRIM24TRIM33
SCHEMBL30995255 0.62 TRIM24 (0.33) TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106432097-A Synthesis method of medical raw material 2-methyl-5-fluorine-6-chloro pyridine-4-ketone 无锡乾浩生物医药有限公司 2017-02-22 CN disclosed