Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.32 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.31 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19950129 | 0.80 | TRIM24 (0.31) | TRIM24TRIM33 | |
| SCHEMBL22445786 | 0.73 | KDM4E (0.35) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL25795312 | 0.73 | KDM4E (0.32) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL31128145 | 0.73 | KDM4E (0.32) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL20487466 | 0.69 | VRK1 (0.32) | — | |
| SCHEMBL31381859 | 0.69 | NOS3 (0.37) | KMT2A | |
| SCHEMBL1044209 | 0.69 | ALDH1A1 (0.35) | KDM4EMEN1ALDH1A1LMNAHPGD | |
| SCHEMBL19792394 | 0.68 | ERN1 (0.38) | ALDH1A1 | |
| SCHEMBL22859511 | 0.68 | CCR1 (0.34) | — | |
| SCHEMBL25928157 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115232109-A | PD-1/PD-L1 small molecule inhibitor and application thereof in medicines | 广东东阳光药业有限公司 | 2022-10-25 | — | — | CN | disclosed |