Known targets — ChEMBL curated mechanism
ABL1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB2AGTR1BCL2BCL2A1BCL2L1BCL2L10BCL2L2BCRBRAFCHRM1CHRNA10CHRNA9DRD1DRD2DRD3DRD4DRD5EGFRF2FLT1FLT4GCKGHSRGNRHRGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHTR1AHTR1BHTR1DHTR2AHTR2CHTR3AIDH2KDRKITMAOBMCL1MTTPPP4HBPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PIKFYVEROCK1ROCK2SLC18A2SLC6A2SLC6A3SLC6A4TACR1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8gyrAgyrBparCparEpol
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28241290 | 0.95 | — | — | |
| SCHEMBL28078277 | 0.90 | — | — | |
| SCHEMBL28075620 | 0.90 | — | — | |
| SCHEMBL28070311 | 0.90 | — | — | |
| SCHEMBL28340137 | 0.90 | — | — | |
| SCHEMBL28082261 | 0.90 | — | — | |
| SCHEMBL28070315 | 0.90 | — | — | |
| SCHEMBL28848964 | 0.90 | — | — | |
| SCHEMBL29291672 | 0.90 | — | — | |
| SCHEMBL28331022 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418502-B | A kind of intermediate and its preparation method and application for synthesizing Paxil | 浙江九洲药业股份有限公司 | 2018-12-14 | — | — | CN | claimed |
| CN-110234671-A | Silicon oxide particle dispersion in polyol | 巴斯夫欧洲公司 | 2019-09-13 | — | — | CN | disclosed |
| CN-110156949-A | Prepare the method and the wherein purposes of stabilizer of Polymer-Polyol Dispersions | 巴斯夫欧洲公司 | 2019-08-23 | — | — | CN | disclosed |
| CN-109563224-A | Stabilizer for dispersion of the polyolefin in polyether polyol | 巴斯夫欧洲公司 | 2019-04-02 | — | — | CN | disclosed |
| CN-106255711-A | Stabilizer for polymer polyol preparation process | 巴斯夫欧洲公司 | 2016-12-21 | — | — | CN | disclosed |