Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 3/20 | 0.41 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL2541472 | 0.92 | HDAC3 (0.43) | EPHX2L3MBTL1PPARGPTPN7DUSP3 | |
| SCHEMBL2549180 | 0.88 | L3MBTL1 (0.45) | EPHX2L3MBTL1PTPN7DUSP3HDAC3 | |
| Trifluoroacetic Acid SCHEMBL2788039 | 0.88 | L3MBTL1 (0.41) | EPHX2L3MBTL1PPARGPTPN7DUSP3 | |
| Trifluoroacetic Acid SCHEMBL2789689 | 0.87 | P2RX7 (0.42) | EPHX2L3MBTL1PPARGPTPN7DUSP3 | |
| Trifluoroacetic Acid SCHEMBL2789992 | 0.87 | P2RX7 (0.41) | EPHX2L3MBTL1PPARGPTPN7DUSP3 | |
| Trifluoroacetic Acid SCHEMBL2788167 | 0.86 | EPHX2 (0.41) | EPHX2L3MBTL1PPARG | |
| SCHEMBL2787720 | 0.84 | EPHX2 (0.41) | EPHX2L3MBTL1PPARGPTPN7DUSP3 | |
| SCHEMBL2807969 | 0.84 | L3MBTL1 (0.41) | EPHX2L3MBTL1PPARGPTPN7DUSP3 | |
| SCHEMBL13165651 | 0.84 | MAPT (0.45) | EPHX2L3MBTL1PPARGPTPN7DUSP3 | |
| Hydrochloric Acid SCHEMBL2786015 | 0.83 | L3MBTL1 (0.41) | EPHX2L3MBTL1PPARGPTPN7DUSP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010097374-A1 | COMPOUNDS FOR USE AS BRADYKININ B1 ANTAGONISTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-02 | — | — | WO | disclosed |