Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Monoethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 5/20 | 0.86 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.86 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.86 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.86 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.72 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.59 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.59 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 1,2-Dipalmitin SCHEMBL23319286 | 1.00 | PRKCA (0.86) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| 1,2-Dipalmitin SCHEMBL23319287 | 1.00 | PRKCA (0.86) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| Ethylene Glycol SCHEMBL22597785 | 0.93 | PRKCA (0.94) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| 1,2-Dipalmitin SCHEMBL7866808 | 0.93 | PRKCA (0.94) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL7061646 | 0.93 | PRKCA (1.00) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL23668326 | 0.93 | PRKCA (1.00) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL23992003 | 0.93 | PRKCA (1.00) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| 1,2-Dipalmitin SCHEMBL594854 | 0.93 | PRKCA (1.00) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL1004733 | 0.93 | PRKCA (1.00) | PRKCAPRKCEPRKCQPRKCDALDH1A1 | |
| SCHEMBL16431424 | 0.93 | PRKCA (1.00) | PRKCAPRKCEPRKCQPRKCDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106470681-A | Supramolecular assembly medicine | 茵维特丝肿瘤学私营有限责任公司 | 2017-03-01 | — | — | CN | disclosed |