Hydrogen Sulfide

Hydrogen Sulfide

SCHEMBL28123731

Cc1ccccc1SNC(N)=O.S

nearest known ligand 0.42

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.42
ALDH1A1 P00352 3/20 0.38
MAPT P10636 3/20 0.38
HPGD P15428 3/20 0.38
MAPK1 P28482 2/20 0.38
HSD17B10 Q99714 1/20 0.38
RAB9A P51151 4/20 0.37
NPC1 O15118 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.36
LMNA P02545 2/20 0.36
TSHR P16473 1/20 0.36
ICAM1 P05362 1/20 0.36
SELE P16581 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NOTUM Q6P988 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
ALOX12 P18054 1/20 0.35
MEN1 O00255 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4206138 0.98 POLB (0.43) POLBALDH1A1MAPTHPGDMAPK1
SCHEMBL28921705 0.84 ALDH1A1 (0.42) POLBALDH1A1MAPTHPGDMAPK1
SCHEMBL29067024 0.79 ALDH1A1 (0.50) POLBALDH1A1MAPTHSD17B10TSHR
SCHEMBL11765865 0.78 MAPT (0.42) POLBALDH1A1MAPTHPGDMAPK1
SCHEMBL9059810 0.78 SMN1; SMN2 (0.42) POLBALDH1A1MAPTHPGDMAPK1
SCHEMBL9332916 0.77 TSHR (0.42) POLBALDH1A1MAPTHPGDHSD17B10
SCHEMBL27661025 0.77 MAPT (0.46) POLBALDH1A1MAPTHPGDMAPK1
SCHEMBL2983050 0.76 ACHE (0.40) ALDH1A1MAPTHSD17B10RAB9ANPC1
SCHEMBL27508834 0.76 IDO1 (0.44) POLBALDH1A1MAPTHSD17B10RAB9A
SCHEMBL27574868 0.76 ALDH1A1 (0.42) POLBALDH1A1MAPK1HSD17B10RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108690384-A Actinic-radiation curable composition, cured coating film and laminated body DIC株式会社 2018-10-23 CN disclosed
CN-106414039-A Three-dimensional object and method of forming the same 株式会社理光 2017-02-15 CN disclosed