SCHEMBL28123734

SCHEMBL28123734

CCCCOC(=O)C(C)(Cc1ccccc1)C(=O)OCCCC

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 6/20 0.58
TSHR P16473 5/20 0.52
ALDH1A1 P00352 4/20 0.52
CYP3A4 P08684 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
MAPK1 P28482 2/20 0.52
TP53 P04637 1/20 0.45
MMP1 P03956 1/20 0.45
MMP9 P14780 1/20 0.45
MMP13 P45452 1/20 0.45
RECQL P46063 1/20 0.44
HSD17B10 Q99714 1/20 0.44
LMNA P02545 2/20 0.44
CETP P11597 3/20 0.43
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
PDE4D Q08499 1/20 0.43
CTSK P43235 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28817686 0.96 MMP8 (0.66) MMP8TSHRALDH1A1CYP3A4TDP1
SCHEMBL31147044 0.95 MMP8 (0.57) MMP8TSHRALDH1A1CYP3A4TDP1
SCHEMBL28003872 0.90 MMP8 (0.61) MMP8TSHRALDH1A1CYP3A4TDP1
SCHEMBL27817293 0.86 TSHR (0.51) MMP8TSHRALDH1A1CYP3A4TDP1
SCHEMBL28147414 0.86 TSHR (0.54) MMP8TSHRALDH1A1CYP3A4TDP1
SCHEMBL14473051 0.85 TSHR (0.50) MMP8TSHRALDH1A1CYP3A4TDP1
SCHEMBL8710582 0.83 MMP8 (0.79) MMP8TSHRALDH1A1L3MBTL1RECQL
SCHEMBL28123739 0.83 TSHR (0.51) MMP8TSHRALDH1A1CYP3A4TDP1
SCHEMBL28123756 0.82 TSHR (0.50) MMP8TSHRALDH1A1CYP3A4TDP1
SCHEMBL28123737 0.82 TSHR (0.50) MMP8TSHRALDH1A1CYP3A4TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106608939-B The preparation method of catalytic component for olefinic polymerization 中国石油化工股份有限公司 2019-08-20 CN claimed
CN-106608940-B The preparation method of catalytic component for olefinic polymerization 中国石油化工股份有限公司 2019-06-28 CN claimed
CN-104558290-B One kind being used for catalyst component for olefin polymerization and catalyst 中国石油化工股份有限公司 2018-11-02 CN claimed
CN-104558291-B One kind is used for olefin polymerization catalysis preparation method 中国石油化工股份有限公司 2017-05-31 CN claimed
CN-104558292-B One kind is used for olefin polymerization catalysis preparation method 中国石油化工股份有限公司 2017-05-31 CN claimed
CN-106608939-A Preparation method of catalyst component for olefin polymerization 中国石油化工股份有限公司 2017-05-03 CN claimed
CN-104558293-B Catalyst component for olefin polymerization and catalyst 中国石油化工股份有限公司 2017-02-15 CN claimed
CN-118909171-A Solid catalyst component for olefin polymerization reaction, preparation method and application thereof 中国石油化工股份有限公司 2024-11-08 CN disclosed
CN-109678997-B Catalyst component and catalyst for olefin polymerization, prepolymerized catalyst and olefin polymerization method 中国石油化工股份有限公司 2021-11-19 CN disclosed
CN-106608939-B The preparation method of catalytic component for olefinic polymerization 中国石油化工股份有限公司 2019-08-20 CN disclosed
CN-106608940-B The preparation method of catalytic component for olefinic polymerization 中国石油化工股份有限公司 2019-06-28 CN disclosed
CN-109678997-A Catalytic component and catalyst and pre-polymerized catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2019-04-26 CN disclosed
CN-104558290-B One kind being used for catalyst component for olefin polymerization and catalyst 中国石油化工股份有限公司 2018-11-02 CN disclosed
CN-104558292-B One kind is used for olefin polymerization catalysis preparation method 中国石油化工股份有限公司 2017-05-31 CN disclosed
CN-106608939-A Preparation method of catalyst component for olefin polymerization 中国石油化工股份有限公司 2017-05-03 CN disclosed
CN-104558293-B Catalyst component for olefin polymerization and catalyst 中国石油化工股份有限公司 2017-02-15 CN disclosed