SCHEMBL28817686

SCHEMBL28817686

CCCCOC(=O)C(C)(Cc1ccccc1)C(=O)OCC

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 7/20 0.66
ALDH1A1 P00352 4/20 0.51
RECQL P46063 1/20 0.51
TSHR P16473 4/20 0.49
TDP1 Q9NUW8 3/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
CYP3A4 P08684 2/20 0.49
MAPK1 P28482 2/20 0.49
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
PIN1 Q13526 1/20 0.43
MMP1 P03956 1/20 0.42
MMP9 P14780 1/20 0.42
MMP13 P45452 1/20 0.42
TP53 P04637 1/20 0.42
HSD17B10 Q99714 1/20 0.41
LMNA P02545 1/20 0.41
CETP P11597 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28123734 0.96 MMP8 (0.58) MMP8ALDH1A1RECQLTSHRTDP1
SCHEMBL31147044 0.91 MMP8 (0.57) MMP8ALDH1A1TSHRTDP1L3MBTL1
SCHEMBL8710582 0.89 MMP8 (0.79) MMP8ALDH1A1RECQLTSHRL3MBTL1
SCHEMBL28004336 0.87 ALDH1A1 (0.52) MMP8ALDH1A1RECQLTSHRTDP1
SCHEMBL28003872 0.86 MMP8 (0.61) MMP8ALDH1A1RECQLTSHRTDP1
SCHEMBL27487924 0.84 ALDH1A1 (0.50) MMP8ALDH1A1RECQLTSHRTDP1
SCHEMBL27817293 0.82 TSHR (0.51) MMP8ALDH1A1RECQLTSHRTDP1
SCHEMBL9526598 0.82 MMP8 (0.73) MMP8ALDH1A1RECQLTSHRPIN1
SCHEMBL28147414 0.82 TSHR (0.54) MMP8ALDH1A1RECQLTSHRTDP1
SCHEMBL14473051 0.81 TSHR (0.50) MMP8ALDH1A1RECQLTSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104558290-A Components of catalyst for polymerization of olefins and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558291-A Preparation method of catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558293-A Catalyst component for olefin polymerization and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558292-A Preparation method of catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-04-29 CN claimed
CN-104558290-A Components of catalyst for polymerization of olefins and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN disclosed
CN-104558291-A Preparation method of catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-04-29 CN disclosed
CN-104558293-A Catalyst component for olefin polymerization and catalyst CHINA PETROLEUM & CHEMICAL 2015-04-29 CN disclosed
CN-104558292-A Preparation method of catalyst for olefin polymerization CHINA PETROLEUM & CHEMICAL 2015-04-29 CN disclosed