Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 3/20 | 0.49 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.47 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.47 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.43 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29086088 | 0.85 | SLC2A1 (0.52) | SLC2A1SLC2A2SLC2A3ALDH1A1CYP2C9 | |
| SCHEMBL30585959 | 0.85 | SLC2A1 (0.52) | SLC2A1SLC2A2SLC2A3ALDH1A1CYP2C9 | |
| SCHEMBL3503998 | 0.84 | PDE10A (0.52) | RBP4MEN1KMT2AMALT1 | |
| SCHEMBL27815937 | 0.80 | CYP1A2 (0.51) | SLC2A1SLC2A2SLC2A3ALDH1A1KDM4E | |
| SCHEMBL3072488 | 0.80 | TRPA1 (0.58) | MALT1 | |
| SCHEMBL13030063 | 0.79 | SLC2A1 (0.48) | RBP4SLC2A1SLC2A2SLC2A3ALDH1A1 | |
| SCHEMBL11359476 | 0.79 | POLB (0.55) | MALT1TP53 | |
| SCHEMBL20339483 | 0.76 | TRPV1 (0.61) | ALDH1A1KMT2A | |
| SCHEMBL8421945 | 0.76 | ALDH1A1 (0.70) | SLC2A1SLC2A2SLC2A3ALDH1A1KDM4E | |
| SCHEMBL239605 | 0.76 | MALT1 (0.61) | KDM4ECYP2C19KMT2AMALT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010054006-A1 | MODULATORS OF CXCR7 | CHEMOCENTRYX, INC. (US) | 2010-05-14 | — | — | WO | disclosed |