Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL19100314 | 0.96 | GLRA1 (0.91) | — | |
| Glycine SCHEMBL2916898 | 0.96 | — | — | |
| Glycine SCHEMBL5163283 | 0.92 | GLRA1 (0.83) | — | |
| Glycine SCHEMBL28107246 | 0.92 | — | — | |
| Glycine SCHEMBL3863155 | 0.92 | — | — | |
| Glycine SCHEMBL4940394 | 0.92 | — | — | |
| Glycine SCHEMBL391786 | 0.91 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL93765 | 0.91 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL3640989 | 0.91 | GLRA1 (1.00) | — | |
| Glycine SCHEMBL2116443 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106317851-A | Composite cable material with glycine and calcium bromide compound particles added | 安徽中润电缆集团股份有限公司 | 2017-01-11 | — | — | CN | claimed |
| CN-106479158-A | Polyurethane and the preparation method of glycine calcium bromide semi-organic crystal composite | 陕西聚洁瀚化工有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106479158-A | Polyurethane and the preparation method of glycine calcium bromide semi-organic crystal composite | 陕西聚洁瀚化工有限公司 | 2017-03-08 | — | — | CN | disclosed |
| CN-106317851-A | Composite cable material with glycine and calcium bromide compound particles added | 安徽中润电缆集团股份有限公司 | 2017-01-11 | — | — | CN | disclosed |