Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.59 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.49 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.49 |
| ▸ | PARP1 | P09874 | 4/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | CHUK | O15111 | 1/20 | 0.40 |
| ▸ | KDM5A | P29375 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SNCA | P37840 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | AOC1 | P19801 | 2/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7380955 | 0.78 | DAO (0.65) | DAOPDE3BPDE3APARP1HRH4 | |
| SCHEMBL12909532 | 0.76 | BRD4 (0.59) | DAOMAPTAOC3 | |
| SCHEMBL19362482 | 0.76 | DAO (0.49) | DAOPDE3BPDE3AHRH4CHUK | |
| SCHEMBL24312093 | 0.75 | DAO (0.61) | DAOPDE3BPDE3APARP1HRH4 | |
| SCHEMBL21957317 | 0.75 | DAO (0.65) | DAOPDE3BPDE3APARP1HRH4 | |
| SCHEMBL31475468 | 0.75 | DAO (0.65) | DAOPDE3BPDE3APARP1HRH4 | |
| SCHEMBL3360519 | 0.75 | DAO (1.00) | DAOPDE3BPDE3APARP1HRH4 | |
| SCHEMBL22017082 | 0.74 | DAO (0.59) | DAOPDE3BPDE3APARP1HRH4 | |
| SCHEMBL4310842 | 0.74 | DAO (0.59) | DAOPDE3BPDE3APARP1HRH4 | |
| SCHEMBL22016192 | 0.74 | DAO (0.59) | DAOPDE3BPDE3APARP1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459034-B | Carbostyril derivative as fibroblast growth factor acceptor inhibitor | 普林斯匹亚生物制药公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-106459034-A | Quinolone derivatives as fibroblast growth factor receptor inhibitors | 普林斯匹亚生物制药公司 | 2017-02-22 | — | — | CN | disclosed |