SCHEMBL28124395

SCHEMBL28124395

[C]#CCCCc1c(I)ccc2ccccc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.36
CYP1A2 P05177 4/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
ALDH1A1 P00352 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
CYP2A6 P11509 2/20 0.34
TSHR P16473 2/20 0.34
KDM4E B2RXH2 3/20 0.34
GAA P10253 2/20 0.34
MAPT P10636 2/20 0.34
TAAR1 Q96RJ0 1/20 0.34
NCEH1 Q6PIU2 1/20 0.33
HPRT1 P00492 1/20 0.32
CYP2D6 P10635 2/20 0.32
GLA P06280 1/20 0.32
HPGD P15428 1/20 0.32
HIF1A Q16665 2/20 0.31
HTR2A P28223 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28239828 0.82 TSHR (0.44) HSD17B10CYP1A2CYP2C19CYP2C9ALDH1A1
SCHEMBL28123924 0.81 CYP2A6 (0.43) HSD17B10CYP1A2CYP2C19CYP2C9ALDH1A1
SCHEMBL1610412 0.80 L3MBTL1 (0.47) HSD17B10CYP1A2CYP2C19CYP2C9ALDH1A1
SCHEMBL28839024 0.77 ALDH1A1 (0.34) HSD17B10CYP1A2CYP2C19ALDH1A1TDP1
SCHEMBL18244906 0.77 KMT2A (0.48) MAPTNCEH1
SCHEMBL1609690 0.75 L3MBTL1 (0.46) HSD17B10CYP1A2CYP2C19CYP2C9ALDH1A1
SCHEMBL3910923 0.74 HSD17B10 (0.41) HSD17B10CYP1A2CYP2C19CYP2C9ALDH1A1
SCHEMBL1611934 0.73 L3MBTL1 (0.44) HSD17B10CYP1A2CYP2C19CYP2C9ALDH1A1
SCHEMBL1610853 0.73 L3MBTL1 (0.44) HSD17B10CYP1A2CYP2C19CYP2C9ALDH1A1
SCHEMBL18245166 0.73 SLC6A4 (0.49) MAPTNCEH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106414461-A BORATE-BASED BASE GENERATOR, AND BASE-REACTIVE COMPOSITION COMPRISING SUCH BASE GENERATOR 和光纯药工业株式会社 2017-02-15 CN disclosed