Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 8/20 | 0.80 |
| ▸ | MAPT | P10636 | 6/20 | 0.80 |
| ▸ | NPC1 | O15118 | 6/20 | 0.80 |
| ▸ | RAB9A | P51151 | 6/20 | 0.80 |
| ▸ | TP53 | P04637 | 3/20 | 0.80 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.80 |
| ▸ | POLB | P06746 | 3/20 | 0.78 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.68 |
| ▸ | HPGD | P15428 | 7/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.68 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | MAOA | P21397 | 2/20 | 0.68 |
| ▸ | MAOB | P27338 | 2/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cladrin SCHEMBL738092 | 0.89 | KDM4E (1.00) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| Calycosin SCHEMBL30335127 | 0.88 | KDM4E (1.00) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| Calycosin SCHEMBL73013 | 0.88 | KDM4E (1.00) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL2069826 | 0.85 | KDM4E (0.84) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL29788255 | 0.85 | KDM4E (0.84) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL12206681 | 0.84 | KDM4E (0.77) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL30238115 | 0.83 | KDM4E (0.83) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| SCHEMBL13904731 | 0.81 | KDM4E (0.77) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| Formononetin SCHEMBL29361145 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10MAPTNPC1RAB9A | |
| Formononetin SCHEMBL15271536 | 0.81 | KDM4E (1.00) | KDM4EHSD17B10MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106279089-A | Formoononetin aliphatic ether analog derivative, its preparation method and medical usage | 南京华迈生物医药科技有限公司 | 2017-01-04 | — | — | CN | disclosed |