Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | CTSS | P25774 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | CTSB | P07858 | 1/20 | 0.47 |
| ▸ | CTSK | P43235 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | XIAP | P98170 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | REN | P00797 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Histidine SCHEMBL10660498 | 0.96 | ACE (0.56) | ACEPTPN1CTSSCTSLCTSB | |
| Phenylalanine Methyl Ester SCHEMBL28846001 | 0.93 | ACE (0.51) | ACEPTPN1CTSSCTSLCTSB | |
| Phenylalanine Methyl Ester SCHEMBL28846004 | 0.90 | ACE (0.46) | ACEPTPN1ATMAPPMAPK1 | |
| SCHEMBL28846075 | 0.89 | ACE (0.53) | ACEPTPN1CTSSCTSLCTSB | |
| SCHEMBL23598225 | 0.89 | ACE (0.57) | ACEPTPN1CTSSCTSLCTSB | |
| SCHEMBL7300127 | 0.89 | ACE (0.57) | ACEPTPN1CTSSCTSLCTSB | |
| SCHEMBL10522069 | 0.89 | ACE (0.57) | ACEPTPN1CTSSCTSLCTSB | |
| Dl-Phenylalanine SCHEMBL28846053 | 0.88 | REN (0.47) | ACEATMAPPMAPK1REN | |
| SCHEMBL1133305 | 0.87 | ITGB3 (0.48) | ACEPTPN1CTSSCTSLCTSB | |
| SCHEMBL214303 | 0.87 | ITGB3 (0.48) | ACEPTPN1CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106309375-B | A kind of nano particle preparations, preparation method and application | 中国科学院过程工程研究所 | 2019-03-26 | — | — | CN | disclosed |
| CN-106309375-A | Nanoparticle preparation, and preparation method and application thereof | 中国科学院过程工程研究所 | 2017-01-11 | — | — | CN | disclosed |