Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | G6PD | P11413 | 1/20 | 0.53 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | LDHA | P00338 | 2/20 | 0.50 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12278579 | 0.92 | LDHA (0.57) | KDM4EKMT2AMAPTG6PDTLR9 | |
| SCHEMBL5106815 | 0.90 | MAPT (0.65) | KDM4EKMT2AMTNR1AMTNR1BMAPT | |
| SCHEMBL22281315 | 0.83 | KDM4E (0.68) | KDM4EKMT2AMTNR1AMTNR1BMAPT | |
| SCHEMBL4874176 | 0.83 | DYRK1A (0.51) | KDM4EKMT2AMAPTG6PDTLR9 | |
| SCHEMBL17033113 | 0.82 | SMN1; SMN2 (0.54) | KDM4EKMT2AMTNR1AMTNR1BMAPT | |
| SCHEMBL4869324 | 0.81 | KDM4E (0.54) | KDM4EKMT2AMTNR1AMTNR1BMAPT | |
| SCHEMBL3776520 | 0.79 | KMT2A (0.65) | KDM4EKMT2AMTNR1AMTNR1BMAPT | |
| SCHEMBL7111037 | 0.78 | MAPT (0.54) | KMT2AMAPTMEN1RAB9ANPC1 | |
| SCHEMBL21698302 | 0.78 | GPR3 (0.54) | KDM4EKMT2AMAPTMEN1RAB9A | |
| SCHEMBL17283743 | 0.77 | GPR3 (0.58) | KDM4EKMT2AMAPTMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106397397-B | Diaryl and episulfide and selenides and its synthesis and application | 华东师范大学 | 2019-02-01 | — | — | CN | claimed |
| CN-106397397-A | Diaryl ring fused sulfides and diaryl ring fused selenides, and synthesis method and application thereof | 华东师范大学 | 2017-02-15 | — | — | CN | claimed |
| CN-106397397-B | Diaryl and episulfide and selenides and its synthesis and application | 华东师范大学 | 2019-02-01 | — | — | CN | disclosed |
| CN-106397397-A | Diaryl ring fused sulfides and diaryl ring fused selenides, and synthesis method and application thereof | 华东师范大学 | 2017-02-15 | — | — | CN | disclosed |