Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | PPARD | Q03181 | 5/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | FABP4 | P15090 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | PPME1 | Q9Y570 | 2/20 | 0.37 |
| ▸ | APEH | P13798 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16916430 | 0.87 | HTR6 (0.55) | HTR6MEN1KMT2AALDH1A1LMNA | |
| SCHEMBL15564770 | 0.80 | L3MBTL1 (0.52) | PPARGPPARDPPARAHTR6MEN1 | |
| SCHEMBL20494319 | 0.77 | PPARG (0.53) | PPARGPPARDPPARAFABP4HTR6 | |
| SCHEMBL27834264 | 0.73 | NR4A1 (0.54) | ALDH1A1HPGDHTTNOTUMPOLB | |
| SCHEMBL30229407 | 0.73 | HTR6 (0.58) | PPARGPPARDPPARAHTR6MEN1 | |
| SCHEMBL14727085 | 0.73 | HTR6 (0.58) | PPARGPPARDPPARAHTR6MEN1 | |
| SCHEMBL30675636 | 0.71 | NOTUM (0.48) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL1352722 | 0.71 | NOTUM (0.48) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL20742914 | 0.70 | HTR6 (0.51) | PPARGPPARDPPARAHTR6MEN1 | |
| SCHEMBL18223168 | 0.70 | KDM4E (0.41) | PPARGPPARAKMT2AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458996-A | Fused pyrimidines as inhibitors of the p97 complex | 克里弗生物科学公司 | 2017-02-22 | — | — | CN | disclosed |