Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 4/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.37 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.35 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.35 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | RBP4 | P02753 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16794015 | 0.81 | BTK (0.60) | BTKEPHX2P2RX7 | |
| SCHEMBL18183922 | 0.75 | BTK (0.54) | BTKEPHX2P2RX7 | |
| SCHEMBL16793886 | 0.72 | BTK (0.66) | BTKEPHX2P2RX7 | |
| SCHEMBL24426173 | 0.72 | BTK (0.69) | BTKEPHX2P2RX7 | |
| SCHEMBL19876260 | 0.70 | BTK (1.00) | BTKEPHX2P2RX7 | |
| SCHEMBL16793935 | 0.70 | BTK (0.47) | BTKEPHX2P2RX7CYP2C9CHRNA7 | |
| SCHEMBL17663698 | 0.68 | KMT2A (0.50) | BTKCHRNA7 | |
| SCHEMBL19892033 | 0.67 | BTK (0.37) | BTKTPSAB1TPSD1TPSG1RBP4 | |
| SCHEMBL31716905 | 0.65 | EPHX2 (0.62) | BTKEPHX2 | |
| SCHEMBL19886208 | 0.65 | BTK (0.36) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109096274-A | It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease | 比奥根MA公司 | 2018-12-28 | — | — | CN | disclosed |
| CN-108947913-A | It can be used for treating the aryl-linking compound of human tumor, neurology and amynologic disease | 比奥根MA公司 | 2018-12-07 | — | — | CN | disclosed |
| CN-106459002-B | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2018-08-21 | — | — | CN | disclosed |
| CN-106459002-A | Biaryl compounds useful in the treatment of human oncological, neurological and immunological diseases | 比奥根MA公司 | 2017-02-22 | — | — | CN | disclosed |