Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PKLR | P30613 | 1/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28133659 | 0.88 | TSHR (0.42) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL28307603 | 0.86 | TSHR (0.43) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL28133676 | 0.84 | TSHR (0.39) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL28134492 | 0.84 | TSHR (0.39) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL28125689 | 0.83 | TSHR (0.41) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL17187607 | 0.80 | TSHR (0.38) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL17187700 | 0.80 | TSHR (0.38) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL28225020 | 0.80 | MMP2 (0.43) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL17161075 | 0.79 | L3MBTL1 (0.39) | TSHRCA1CA2MMP1MMP2 | |
| SCHEMBL17187611 | 0.79 | L3MBTL1 (0.39) | TSHRCA1CA2MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458955-B | Aryl substituted heterocyclyl sulfones | 格吕伦塔尔有限公司 | 2019-07-19 | — | — | CN | disclosed |
| CN-106458955-A | Aryl substituted heterocyclyl sulfones | 格吕伦塔尔有限公司 | 2017-02-22 | — | — | CN | disclosed |