Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | RAB9A | P51151 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | MTOR | P42345 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5373992 | 0.97 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL7130164 | 0.84 | SMN1; SMN2 (0.68) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL5455503 | 0.80 | KDM4E (0.70) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL6964732 | 0.79 | NPC1 (0.54) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL1520344 | 0.78 | SMN1; SMN2 (0.71) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL27283642 | 0.78 | RAB9A (0.60) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL6953393 | 0.77 | SMN1; SMN2 (0.52) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL9372216 | 0.77 | ALDH1A1 (0.48) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL6952650 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA | |
| SCHEMBL6964811 | 0.77 | SMN1; SMN2 (0.48) | SMN1; SMN2ALDH1A1RAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106458993-A | Imide-based proteolytic modulators and related methods of use | 阿尔维纳斯股份有限公司 | 2017-02-22 | — | — | CN | disclosed |