Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.34 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928351 | 1.00 | PDK2 (0.34) | PDK2LRRK2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL7161249 | 0.92 | ALDH1A1 (0.35) | PDK2KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1927398 | 0.87 | LRRK2 (0.34) | LRRK2KDM4EALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL1452454 | 0.83 | PDK2 (0.37) | PDK2LRRK2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL1571002 | 0.83 | PDK2 (0.38) | PDK2KDM4EALDH1A1 | |
| SCHEMBL1809551 | 0.82 | PDK2 (0.46) | PDK2KDM4EALDH1A1MAPTTDP1 | |
| SCHEMBL27918584 | 0.81 | PDK2 (0.35) | PDK2LRRK2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL14455138 | 0.80 | MTNR1A (0.39) | — | |
| SCHEMBL12284007 | 0.80 | PDK2 (0.41) | PDK2LRRK2KDM4EALDH1A1CYP1A2 | |
| SCHEMBL15399801 | 0.79 | MEN1 (0.36) | PDK2KDM4EALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106432314-A | Two-photon fluorescent dye based on 4-methoxyphenyl-substituted BODIPY and diphenylaminofluorene and synthesis method of two-photon fluorescent dye | 国家烟草质量监督检验中心 | 2017-02-22 | — | — | CN | claimed |