Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 13/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.57 |
| ▸ | F2 | P00734 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL254113 | 0.88 | F10 (0.72) | F10KCNH2F2 | |
| Hydrochloric Acid SCHEMBL160886 | 0.87 | F10 (0.71) | F10KCNH2F2 | |
| SCHEMBL6694260 | 0.81 | KCNH2 (0.64) | F10KCNH2F2 | |
| SCHEMBL6714358 | 0.80 | F10 (0.69) | F10KCNH2F2NPC1RAB9A | |
| SCHEMBL805112 | 0.78 | RAB9A (0.58) | F10KCNH2F2NPC1RAB9A | |
| SCHEMBL13645063 | 0.78 | RAB9A (0.57) | F10KCNH2F2NPC1RAB9A | |
| SCHEMBL890632 | 0.77 | F10 (0.71) | F10KCNH2TMPRSS4 | |
| SCHEMBL6694262 | 0.77 | F10 (0.63) | F10KCNH2F2 | |
| SCHEMBL14366426 | 0.77 | F10 (0.58) | F10KCNH2F2NPC1RAB9A | |
| SCHEMBL10177863 | 0.77 | F10 (0.57) | F10KCNH2F2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106518758-A | Preparation method of Betrixaban intermediate N-(5-chloro-2-pyridyl)-2-(4-cyanobenzeneformamido)-5-metoxybenzamide | 扬子江药业集团江苏紫龙药业有限公司 | 2017-03-22 | — | — | CN | disclosed |