SCHEMBL28126708

SCHEMBL28126708

Cc1cc(C)c(N)c(S)c1N

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.50
TSHR P16473 4/20 0.50
CYP3A4 P08684 3/20 0.50
TDP1 Q9NUW8 3/20 0.50
TP53 P04637 1/20 0.50
MAPK1 P28482 1/20 0.43
POLB P06746 2/20 0.42
KDM4E B2RXH2 2/20 0.34
CD44 P16070 2/20 0.32
CASP1 P29466 1/20 0.32
NOS3 P29474 1/20 0.31
NOS1 P29475 1/20 0.31
NOS2 P35228 1/20 0.31
GAA P10253 3/20 0.30
MAPT P10636 2/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28370423 0.88 TSHR (0.46) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL19972039 0.86 CYP3A4 (0.43) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL28243411 0.82 TSHR (0.46) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL28716253 0.78 ALDH1A1 (0.42) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL487173 0.75 ALDH1A1 (0.58) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL28365814 0.75 CYP3A4 (0.43) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL19972015 0.75 CYP3A4 (0.38) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL262306 0.73 ALDH1A1 (0.56) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL104361 0.73 POLB (0.48) ALDH1A1TSHRCYP3A4TDP1TP53
SCHEMBL5185462 0.71 ALDH1A1 (0.53) ALDH1A1TSHRCYP3A4TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107880259-A A kind of method of online modified carbon dioxide epoxy propane copolymer 中国科学院长春应用化学研究所 2018-04-06 CN claimed
CN-109792093-A Deformation detection sensor for sealed secondary battery, and sealed secondary battery 通伊欧轮胎株式会社 2019-05-21 CN disclosed
CN-109790274-A URETHANE RESIN USING POLYROTAXANE, AND POLISHING PAD 株式会社德山 2019-05-21 CN disclosed
CN-109690856-A Utilize the manufacturing method and battery pack of the battery pack of used battery 通伊欧轮胎株式会社 2019-04-26 CN disclosed
CN-109689294-A Polishing pad 霓达哈斯股份有限公司 2019-04-26 CN disclosed
CN-106165145-B Enclosed secondary battery deformation detection sensor 东洋橡胶工业株式会社 2018-10-30 CN disclosed
CN-108351384-A Method for predicting remaining capacity of sealed secondary battery, system for predicting remaining capacity, method for acquiring battery internal information, and battery control method 东洋橡胶工业株式会社 2018-07-31 CN disclosed
CN-108124449-A Primer-free two-component polyurethane adhesive 伊利诺斯工具制品有限公司 2018-06-05 CN disclosed
CN-104919271-B Sensor and method for manufacturing the same 东洋橡胶工业株式会社 2017-08-15 CN disclosed
CN-104781230-B Sulfur-containing polyaromatic polyamines useful for polyurea synthesis 米其林集团总公司 2017-08-01 CN disclosed
CN-104736982-B Sensor and its manufacture method 东洋橡胶工业株式会社 2017-07-14 CN disclosed
CN-106716707-A SENSOR FOR DETECTING DEFORMATION OF SEALED SECONDARY BATTERY 东洋橡胶工业株式会社 2017-05-24 CN disclosed
CN-106716052-A Method for manufacturing displacement detection sensor for sealed-type secondary battery 东洋橡胶工业株式会社 2017-05-24 CN disclosed
CN-106662425-A Sensor for monitoring sealed secondary battery, sealed secondary battery, and method for monitoring sealed secondary battery 东洋橡胶工业株式会社 2017-05-10 CN disclosed
CN-106471385-A The deterioration diagnosis method of enclosed secondary battery and deterioration diagnostic system 东洋橡胶工业株式会社 2017-03-01 CN disclosed
CN-106463797-A Method for detecting deformation of sealed secondary battery and sealed secondary battery 东洋橡胶工业株式会社 2017-02-22 CN disclosed
CN-106457509-A Polishing pad and method for manufacturing the same 罗门哈斯电子材料CMP控股股份有限公司 2017-02-22 CN disclosed
CN-106463795-A Deformation detection sensor for sealed secondary battery, sealed secondary battery, and deformation detection method for sealed secondary battery 东洋橡胶工业株式会社 2017-02-22 CN disclosed
CN-106066151-A Deformation detection sensor and manufacture method thereof 东洋橡胶工业株式会社 2016-11-02 CN disclosed
CN-106065058-A Deformation detection sensor and manufacture method thereof 东洋橡胶工业株式会社 2016-11-02 CN disclosed