Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28126708 | 0.86 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1TP53TDP1 | |
| SCHEMBL28716253 | 0.82 | ALDH1A1 (0.42) | CYP3A4TSHRALDH1A1TP53TDP1 | |
| SCHEMBL1610330 | 0.80 | CYP3A4 (0.33) | CYP3A4TSHRMAPK1 | |
| SCHEMBL19972015 | 0.79 | CYP3A4 (0.38) | CYP3A4TSHRALDH1A1TP53TDP1 | |
| SCHEMBL28370423 | 0.76 | TSHR (0.46) | CYP3A4TSHRALDH1A1TP53TDP1 | |
| SCHEMBL28243411 | 0.76 | TSHR (0.46) | CYP3A4TSHRALDH1A1TP53TDP1 | |
| SCHEMBL24522014 | 0.75 | CYP3A4 (0.30) | CYP3A4TSHRMAPK1 | |
| SCHEMBL394882 | 0.75 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1TP53TDP1 | |
| SCHEMBL29738345 | 0.75 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1TP53TDP1 | |
| SCHEMBL2131880 | 0.75 | ALDH1A1 (0.50) | CYP3A4TSHRALDH1A1TP53TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957241-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | WEE1, WEE2, WASF2 | CYP3A4 933/4885TSHR 4030/4885ALDH1A1 544/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.