SCHEMBL28126755

SCHEMBL28126755

CC(=O)Cn1cnc2cncnc21

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.55
HDAC1 Q13547 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51
LTA4H P09960 1/20 0.41
PDE4A P27815 2/20 0.38
PDE4B Q07343 2/20 0.38
PDE4C Q08493 2/20 0.38
PDE4D Q08499 2/20 0.38
ADORA2A P29274 1/20 0.38
ADORA2B P29275 1/20 0.38
NPC1 O15118 2/20 0.36
RAB9A P51151 2/20 0.36
POLB P06746 1/20 0.36
DNMT3B Q9UBC3 1/20 0.35
ALDH1A1 P00352 4/20 0.35
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 3/20 0.35
CYP2C19 P33261 3/20 0.35
LMNA P02545 2/20 0.35
TSHR P16473 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1692456 0.85 FDPS (0.56) FDPSHDAC1HDAC6LTA4HADORA2B
SCHEMBL6948592 0.84 FDPS (0.55) FDPSHDAC1HDAC6LTA4HNPC1
SCHEMBL28313408 0.81 FDPS (0.49) FDPSHDAC1HDAC6LTA4HNPC1
SCHEMBL29941724 0.78 FDPS (0.54) FDPSHDAC1HDAC6LTA4HADORA2A
SCHEMBL5062453 0.78 FDPS (0.54) FDPSHDAC1HDAC6LTA4HADORA2A
SCHEMBL1797755 0.77 FDPS (0.51) FDPSHDAC1HDAC6LTA4HADORA2A
SCHEMBL5033561 0.77 FDPS (0.48) FDPSHDAC1HDAC6ALDH1A1CYP2C19
SCHEMBL28615898 0.76 AHCY (0.55) FDPSHDAC1HDAC6LTA4HDNMT3B
Hydrochloric Acid SCHEMBL21174543 0.76 FDPS (0.53) FDPSHDAC1HDAC6LTA4HADORA2A
SCHEMBL28182252 0.76 FDPS (0.50) FDPSHDAC1HDAC6LTA4HDNMT3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104710424-B (R) (+) preparation method of 9 (2 hydroxypropyl) adenine 河南师范大学 2017-03-01 CN claimed
CN-116609445-A Acyclic nucleoside phosphonate compound and preparation method, analysis method and application thereof 上海医药工业研究院有限公司 2023-08-18 CN disclosed
CN-104710424-B (R) (+) preparation method of 9 (2 hydroxypropyl) adenine 河南师范大学 2017-03-01 CN disclosed
CN-104710424-B (R) (+) preparation method of 9 (2 hydroxypropyl) adenine 河南师范大学 2017-03-01 CN disclosed