SCHEMBL28128

SCHEMBL28128

C1CC2CNCC12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1977605 1.00
Hydrochloric Acid SCHEMBL15539349 0.96
SCHEMBL879636 0.87
SCHEMBL19090363 0.84
SCHEMBL16877333 0.84 CCR5 (0.47)
Hydrochloric Acid SCHEMBL30224904 0.84
SCHEMBL8542060 0.84
SCHEMBL4555410 0.84
SCHEMBL3721399 0.84
SCHEMBL3721400 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 964 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4688792-A1 KRAS INHIBITORS Eli Lilly and Company (US) 2026-02-11 EP claimed
EP-4688784-A1 KRAS INHIBITORS Eli Lilly and Company (US) 2026-02-11 EP claimed
US-12479827-B2 Heteroaromatic carboxamide derivatives as plasma kallikrein inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2025-11-25 US claimed
EP-4648763-A2 COMPOUNDS FOR FGFRS INHIBITORS Cogent Biosciences, Inc. (US) 2025-11-19 EP claimed
CN-116120287-B Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein 勃林格殷格翰国际有限公司 2025-01-28 CN claimed
US-20240368193-A1 KRAS INHIBITORS ELI LILLY AND COMPANY 2024-11-07 US claimed
US-20240343736-A1 KRAS INHIBITORS ELI LILLY AND COMPANY 2024-10-17 US claimed
WO-2024206766-A1 KRAS INHIBITORS ELI LILLY AND COMPANY (US) 2024-10-03 WO claimed
WO-2024206747-A1 KRAS INHIBITORS ELI LILLY AND COMPANY (US) 2024-10-03 WO claimed
US-20240270741-A1 COMPOUNDS FOR FGFRS INHIBITORS COGENT BIOSCIENCES, INC. 2024-08-15 US claimed
US-6028073-A N-substituted 3-azabicyclo (3.2.0)heptane derivatives useful as neuroleptics BASF AKTIENGESELLSCHAFT (DE) 2000-02-22 US claimed
US-5753690-A N-substituted azobicycloheptane derivatives, the preparation and use thereof BASF AKTIENGESELLSCHAFT (DE) 1998-05-19 US claimed
EP-0647231-B1 N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS, ETC. BASF AG (DE) 1997-08-27 EP claimed
EP-0775113-A1 N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USEFUL AS NEUROLEPTICS BASF AKTIENGESELLSCHAFT (DE) 1997-05-28 EP claimed
US-5616705-A N-substituted azabicycloheptane derivatives, their preparation and use BASF AKTIENGESELLSCHAFT (DE) 1997-04-01 US claimed
EP-0646113-B1 SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATES USEFUL AS INTERMEDIATE PRODUCTS BASF AG (DE) 1996-12-18 EP claimed
EP-0646110-B1 N-SUBSTITUTED 3-AZABICYCLO[3.2.0]HEPTANE DERIVATIVES USEFUL AS NEUROLEPTIC AGENTS BASF AG (DE) 1996-10-23 EP claimed
US-5521209-A N-substituted azabicyclo[3.2.0]heptane derivatives as neuroleptics, the preparation and use thereof BASF AKTIENGESELLSCHAFT (DE) 1996-05-28 US claimed
WO-1996004245-A1 N-SUBSTITUTED AZABICYCLOHEPTANE DERIVATIVES USEFUL AS NEUROLEPTICS BASF AKTIENGESELLSCHAFT (DE) 1996-02-15 WO claimed
US-5475105-A N-substituted azabicycloheptane derivatives BASF AKTIENGESELLSCHAFT (DE) 1995-12-12 US claimed