⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30224904 | 0.96 | — | — | |
| SCHEMBL28128 | 0.87 | — | — | |
| SCHEMBL1977605 | 0.87 | — | — | |
| SCHEMBL231562 | 0.87 | — | — | |
| SCHEMBL22823872 | 0.87 | — | — | |
| SCHEMBL31727565 | 0.87 | — | — | |
| SCHEMBL1540946 | 0.87 | — | — | |
| SCHEMBL20757480 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL15539349 | 0.83 | — | — | |
| Bromide SCHEMBL3714716 | 0.82 | CCR5 (0.90) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11253499-B2 | Compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-02-22 | — | — | US | disclosed |
| US-20200170997-A1 | NOVEL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2020-06-04 | — | — | US | disclosed |
| EP-3083600-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | Janssen Pharmaceutica NV (BE) | 2016-10-26 | — | — | EP | disclosed |
| WO-2015095011-A1 | IMIDAZOLIN-5-ONE DERIVATIVE USEFUL AS FASN INHIBITORS FOR THE TREATMENT OF CANCER | JANSSEN PHARMACEUTICA NV (BE) | 2015-06-25 | — | — | WO | disclosed |