Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.50 |
| ▸ | BLM | P54132 | 3/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | MTOR | P42345 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16517900 | 0.86 | CYP19A1 (0.70) | CYP19A1CHRM3CHRM2CHRM1LMNA | |
| SCHEMBL4297790 | 0.86 | CYP19A1 (0.70) | CYP19A1CHRM3CHRM2CHRM1LMNA | |
| SCHEMBL9667211 | 0.84 | CHRM3 (0.64) | CHRM3CHRM2CHRM1LMNACHRM4 | |
| SCHEMBL10901068 | 0.84 | CYP19A1 (0.73) | CYP19A1CHRM3CHRM2CHRM1LMNA | |
| SCHEMBL17294713 | 0.83 | LMNA (0.59) | CHRM3CHRM2CHRM1LMNACHRM4 | |
| SCHEMBL17294710 | 0.83 | LMNA (0.59) | CHRM3CHRM2CHRM1LMNACHRM4 | |
| SCHEMBL19624637 | 0.77 | CHRM3 (0.42) | CHRM3CHRM2CHRM1LMNACHRM4 | |
| SCHEMBL22373048 | 0.77 | LMNA (0.41) | LMNACYP2D6MEN1KMT2ATSHR | |
| SCHEMBL3784334 | 0.77 | CHRM3 (0.45) | CHRM3CHRM2CHRM1LMNACHRM4 | |
| SCHEMBL3842006 | 0.77 | CHRM3 (0.45) | CHRM3CHRM2CHRM1LMNACHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106413717-A | Pharmaceutical compositions | 查尔斯顿实验室公司 | 2017-02-15 | — | — | CN | disclosed |